deadline.com – Megan Masters is an AwardsLine contributor. Having portrayed some of Hollywood’s fiercest funny women, Christina Applegate has never shined or elicited as many laughs as she did this season on NBC’s freshman comedy Up All Night. The Emmy-seasoned actress (winning in 2003 and nominated again in 2004 for her guest-starring role as Rachel’s kid sister on Friends and later receiving two lead actress nominations for Samantha Who?) drew inspiration from her own personal experiences to bring life to Reagan Brinkley, a smart, witty and grounded working mom.
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